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FORMULATION AND EVALUATION OF FDTS USING AEGLE MARMELOS AS A NATURAL SUPER-DISINTEGRANTS

AUTHORS:
Mayuri Patil
Suvarna Shelke
Dhanashri Bhangare
Prajakta Shinde
Dr. Manisha Gavit
Dr. Rajesh Wankhede
Mentor
Affiliation
Department of Pharmaceutics, SMBT College of Pharmacy, Nandi Hills, Dhamangaon,Nashik, Maharashtra.
DOI: 10.55041/ijsmt.v2i3.293
CC BY 4.0 License:
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract

The current study uses Aegle marmelos as a natural superdisintegrant in the formulation and assessment of fast-dissolving tablets (FDTs). FDTs improve patient compliance, beginning of action, and therapeutic efficacy since they dissolve quickly in the oral cavity without the need for water. Despite their widespread use, synthetic superdisintegrants like crospovidone and sodium starch glycolate have various drawbacks, such as increased expense, possible irritation, and environmental issues. As a result, interest in natural substitutes is growing.


The medicinal plant Aegle marmelos (Bael; Rutaceae) has good swelling and binding qualities and is rich in mucilage. In this work, the disintegration efficiency of tablet formulations containing mucilage derived from Aegle marmelos is assessed. Evaluation factors such disintegration time, hardness, friability, and weight fluctuation are measured for the manufactured tablets.


The goal of the project is to prove that Aegle marmelos is an efficient, affordable, and environmentally friendly superdisintegrant that can quickly disintegrate tablets with adequate mechanical strength and aid in the creation of sustainable pharmaceutical excipients.

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PUBLICATION DETAILS
Review Type:
Double-Blind Peer Review
License:
CC BY-NC 4.0
Volume/Issue:
Volume 02, Issue 03
Review Rounds:
2
Article Type:
Research Article
Publication Date:
Mar 27 2026
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Patil, M., Shelke, S., Bhangare, D., Shinde, P., Gavit, M. & Wankhede, R. (2026). Formulation and Evaluation of FDTs using Aegle Marmelos as a Natural Super-Disintegrants. International Journal of Science, Strategic Management and Technology, 02(03). https://doi.org/10.55041/ijsmt.v2i3.293

Patil, Mayuri, et al.. "Formulation and Evaluation of FDTs using Aegle Marmelos as a Natural Super-Disintegrants." International Journal of Science, Strategic Management and Technology, vol. 02, no. 03, 2026, pp. . doi:https://doi.org/10.55041/ijsmt.v2i3.293.

Patil, Mayuri,Suvarna Shelke,Dhanashri Bhangare,Prajakta Shinde,Manisha Gavit, and Rajesh Wankhede. "Formulation and Evaluation of FDTs using Aegle Marmelos as a Natural Super-Disintegrants." International Journal of Science, Strategic Management and Technology 02, no. 03 (2026). https://doi.org/https://doi.org/10.55041/ijsmt.v2i3.293.

References
[1]      M. Ratnaparkhi, K. G.R., and A. R.S., “Natural Polymers in Fast Dissolving Tablets,” Res. J. Pharm. Technol., pp. 2859–2866, Nov. 2021, doi: 10.52711/0974-360X.2021.00503.

[2]   P. Upadhyay, . K., P. Chaudhary, and S. Upadhyay, “A Review on Formulation and Evaluation Approaches for Fast Release Tablet,” Mathews Journal of Pharmaceutical Science, vol. 7, no. 1, Jan. 2023, doi: 10.30654/mjps.10015.

[3]   N. A. * Maner and Shinde A D, “Issue:4 Citation,” 2022. [Online]. Available: www.ijppr.humanjournals.com

[4]   S. U. Kankanamge, A. G. K. Neranja, and K. D. S. Sandarenu, “Mini-review on Natural Disintegrants in Pharmaceutical Formulations,” Journal of Complementary and Alternative Medical Research, pp. 52–56, Jun. 2021, doi: 10.9734/jocamr/2021/v14i230243.

[5]   N. Thapa, G. Parveen, and P. Kumar Ashok, “A COMPREHENSIVE REVIEW ON USE OF NATURAL POLYMERS IN MOUTH DISSOLVING TABLETS AS SUPERDISINTEGRANTS,” JETIR, 2022. [Online]. Available: www.jetir.orga242

[6]   F. Joseph and K. Premaletha, “Natural Superdisintegrants for the Formulation of Orally Disintegrating Tablets,” International Journal of Research and Review, vol. 8, no. 11, pp. 123–128, Nov. 2021, doi: 10.52403/ijrr.20211117.

[7]   S. B. Shirsand, V. Jonathan, S. B. Shirsand, V. Jonathan, P. S. Potdar, and S. S. Shirsand, “Aegle marmelos as a disintegrant in design of fast dissolving tablets,” 2016. [Online]. Available: https://www.researchgate.net/publication/316472560

[8]   A. Banerjee et al., “A Review: Medicinal Properties and Health Benefits of Bael (Aegle marmelos),” J. Sci. Res. Rep., vol. 30, no. 6, pp. 773–786, Jun. 2024, doi: 10.9734/jsrr/2024/v30i62094.
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This article has undergone plagiarism screening and double-blind peer review. Editorial policies have been followed. Authors retain copyright under CC BY-NC 4.0 license. The research complies with ethical standards and institutional guidelines.
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