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International Journal of Science, Strategic Management and Technology

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ISSN: 3108-1762 (Online)
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A PERSONALIZED HEALTHCARE ANALYTICS FRAMEWORK FOR EARLY CARDIOVASCULAR RISK PREDICTION USING EXPLAINABLE MACHINE LEARNING

AUTHORS:
Shaik Ishma
Mentor
Affiliation
Department of Computer Science and Engineering,

Malla Reddy College of Engineering and Technology (MRCET), Hyderabad, Telangana, India.
CC BY 4.0 License:
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Cardiovascular diseases are a major global health concern, requiring early risk identification and effective preventive healthcare strategies. Traditional assessment methods rely on clinical measurements, medical history, and expert interpretation, which may limit the identification of complex relationships among patient attributes. This research proposes a Personalized Healthcare Analytics Framework for Early Cardiovascular Risk Prediction Using Explainable Machine Learning. The framework applies data preprocessing techniques, including missing-value handling, feature encoding, normalization, and exploratory data analysis, to improve data quality. Feature selection methods identify relevant clinical attributes for model development. Multiple machine learning algorithms, including Logistic Regression, Random Forest, Support Vector Machine, and XGBoost, are trained and evaluated using appropriate performance metrics. An ensemble learning approach combines complementary model predictions to improve predictive performance. Probability calibration assesses the reliability of estimated risk scores, while SHAP-based explanations identify influential clinical features at both global and individual patient levels. Model performance is evaluated using accuracy, precision, recall, F1-score, ROC-AUC, and calibration metrics. The proposed framework aims to support interpretable cardiovascular risk assessment and assist healthcare professionals in making informed preventive decisions.

 

Keywords: Cardiovascular Risk Prediction, Explainable Machine Learning, Ensemble Learning, Feature Selection, SHAP Explainability, Personalized Healthcare.
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Ishma, S. (2025). A Personalized Healthcare Analytics Framework for Early Cardiovascular Risk Prediction Using Explainable Machine Learning. International Journal of Science, Strategic Management and Technology, Volume 01(01), 1-9. https://doi.org/10.55041/ijsmt.v1i1.014

Ishma, Shaik. "A Personalized Healthcare Analytics Framework for Early Cardiovascular Risk Prediction Using Explainable Machine Learning." International Journal of Science, Strategic Management and Technology, vol. Volume 01, no. 01, 2025, pp. 1-9. doi:https://doi.org/10.55041/ijsmt.v1i1.014.

Ishma, Shaik. "A Personalized Healthcare Analytics Framework for Early Cardiovascular Risk Prediction Using Explainable Machine Learning." International Journal of Science, Strategic Management and Technology Volume 01, no. 01 (2025): 1-9. https://doi.org/https://doi.org/10.55041/ijsmt.v1i1.014.

References

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  • Kumar, K. K. Gola, N. Jee, and B. M. Singh, “Optimized feature fusion-based modified cascaded kernel extreme learning machine for heart disease prediction in E-healthcare,” Computer Methods in Biomechanics and Biomedical Engineering, vol. 27, no. 8, pp. 980–993, 2024, doi: 10.1080/10255842.2023.2218520.

  • Jainul Fathima and M. M. Noor Fasla, “A comprehensive review on heart disease prognostication using different artificial intelligence algorithms,” Computer Methods in Biomechanics and Biomedical Engineering, vol. 27, no. 11, pp. 1357–1374, 2024, doi: 10.1080/10255842.2024.2319706.

  • K. Jalepalli et al., “Development and validation of multicentre study on novel artificial intelligence-based cardiovascular risk score (AICVD),” Family Medicine and Community Health, vol. 12, suppl. 1, Art. no. e002340, 2024, doi: 10.1136/fmch-2023-002340.

  • M. Molenaar et al., “Explainable machine learning using echocardiography to improve risk prediction in patients with chronic coronary syndrome,” European Heart Journal–Digital Health, vol. 5, no. 2, pp. 170–182, 2024, doi: 10.1093/ehjdh/ztae001.

  • M. Salih et al., “A review of evaluation approaches for explainable AI with applications in cardiology,” Artificial Intelligence Review, vol. 57, Art. no. 240, 2024.

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Ethics and Compliance
✓ All ethical standards met
This article has undergone plagiarism screening and double-blind peer review. Editorial policies have been followed. Authors retain copyright under CC BY-NC 4.0 license. The research complies with ethical standards and institutional guidelines.
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