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POLYMERIC MICROSPONGES: SYNTHESIS, CHARACTERIZATION, AND PHARMACEUTICAL APPLICATIONS

AUTHORS:
Mrunmayi Vinod Nikam
Suvarna J. Shelke
Kedar R. Rajapure
Krishna A. Shahane
Mentor
Affiliation
Department of Pharmaceutics, SMBT College of Pharmacy, Dhamangaon, Nashik, Maharashtra, India-422403. Affiliated with Savitribai Phule Pune University.
DOI: 10.55041/ijsmt.v2i3.251
CC BY 4.0 License:
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract

Polymeric microsponges are a way to deliver drugs to the body. These microsponges are porous and interlinked in a special way. They come in sizes from very small to a bit bigger like 5 to 300 μm. Entrapped API within the porous polymeric network and release in a controlled manner.


Polymeric microsponges enhance the physicochemical and chemical stability of labile drugs by protecting them from photodegradation , oxidation and reduction. They also reduce the effects that some medicines can have. The significance is that polymeric microsponges can deliver the medicine right where it is needed especially when we use them in creams or for oral administration. This review examines their historical development, fabrication techniques, characterization methods, drug loading and release mechanisms, diverse applications, advantages, limitations, regulatory considerations, and emerging trends, drawing on recent advancements to highlight their potential in pharmaceutical sciences.[4][5]

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PUBLICATION DETAILS
Review Type:
Double-Blind Peer Review
License:
CC BY-NC 4.0
Volume/Issue:
Volume 02, Issue 03
Review Rounds:
2
Article Type:
Research Article
Publication Date:
Mar 26 2026
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Nikam, M. V., Shelke, S. J., Rajapure, K. R. & Shahane, K. A. (2026). Polymeric Microsponges: Synthesis, Characterization, and Pharmaceutical Applications. International Journal of Science, Strategic Management and Technology, 02(03). https://doi.org/10.55041/ijsmt.v2i3.251

Nikam, Mrunmayi, et al.. "Polymeric Microsponges: Synthesis, Characterization, and Pharmaceutical Applications." International Journal of Science, Strategic Management and Technology, vol. 02, no. 03, 2026, pp. . doi:https://doi.org/10.55041/ijsmt.v2i3.251.

Nikam, Mrunmayi,Suvarna Shelke,Kedar Rajapure, and Krishna Shahane. "Polymeric Microsponges: Synthesis, Characterization, and Pharmaceutical Applications." International Journal of Science, Strategic Management and Technology 02, no. 03 (2026). https://doi.org/https://doi.org/10.55041/ijsmt.v2i3.251.

References
[1] PMC. Microsponges: A novel strategy for drug delivery system. https://pmc.ncbi.nlm.nih.gov/articles/PMC3255415/ DOI: 10.4103/0973-8398.94037 (approx., inferred)

[2] PubMed. Microsponges as Drug Delivery System: Past, Present, and Future... PMID: 37013425 DOI: 10.2174/9789815040408123010008 (bentham)

[3] Liebertpub. Microsponges: Development, Characterization, and Key... DOI: 10.1089/adt.2023.052 [3]

[4] GSCBPS. Design development and evaluation of controlled release micro... https://gsconlinepress.com/journals/gscbps/sites/default/files/GSCBPS-2025-0178.pdf

[5] Taylor & Francis. Polymeric microsponges: an emerging prospect in topical delivery... DOI: 10.1080/00914037.2023.2235872

[6] Pharmajournal. A brief review of microsponges: An update. https://www.thepharmajournal.com/archives/2017/vol6issue5/PartC/6-5-15-269.pdf

[7] PMC. Fabrication, characterization, and evaluation of microsponge... https://pmc.ncbi.nlm.nih.gov/articles/PMC4804404/ DOI: 10.4103/2231-4040.172655 (approx.)

[9] TURCOMAT. A Review On Different Methods Development Approaches Of Micro... https://turcomat.org/index.php/turkbilmat/article/download/11297/8357

[10] IAJPR. MICROSPONGES – A COMPREHENSIVE REVIEW. https://iajpr.com/iajprfiles/uploaddir/190604_DOI.pdf
Ethics and Compliance
✓ All ethical standards met
This article has undergone plagiarism screening and double-blind peer review. Editorial policies have been followed. Authors retain copyright under CC BY-NC 4.0 license. The research complies with ethical standards and institutional guidelines.
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