BIOCHEMICAL AND PHYSIOLOGICAL EFFECTS OF VOLATILE ORGANIC COMPOUNDS EMITTED BY OCIMUM TENUIFLORUM ON HUMAN STRESS BIOMARKER
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This study investigates the effects of Ocimum tenuiflorum (Tulsi) volatile organic compound (VOC) emission on human stress indicators from a biochemical and physiological perspective. This study presents an analysis of the relationships between the neuroendocrine and autonomic pathways involved in stress regulation and the three main volatile organic compounds (VOCs) found in Tulsi–eugenol, linalool, and methyl chavicol–based on secondary data derived from experiments, clinical trials, and reviews. The traditional therapeutic status of Tulsi as an adaptogen is supported by research showing that inhaling the volatile organic compound (VOC) from the plant may affect cortisol activity, improve heart rate variability, decrease oxidative stress, and provide soothing psychological effects. Antioxidant, anti-inflammatory, and neuroprotective benefits are only a few of the broader areas of pharmacological action discussed in the study; taken collectively, they help the body deal with chronic stress. Concerning long-term safety, dose-response relationships, and the need for standardised exposure procedures, there are still significant knowledge gaps. Results from much of the existing studies are not easily generalisable because of the small sample sizes, limited intervention durations, or animal models used. In conclusion, the study states that Tulsi volatile oil compounds (VOCs) show promise as non-invasive, supplementary approaches to stress treatment; nonetheless, it stresses the need for well-designed clinical trials that include biochemical, physiological, and psychological evaluations. Verifying the facts would pave the way for the ethical integration of aromatherapy methods derived from Tulsi into integrative and preventative healthcare paradigms.
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Pandey, V. & Kanyal, S. (2026). Biochemical and Physiological Effects of Volatile Organic Compounds Emitted by Ocimum Tenuiflorum on Human Stress Biomarker. International Journal of Science, Strategic Management and Technology, 02(04). https://doi.org/10.55041/ijsmt.v2i4.302
Pandey, Vivaswaan, and Sapana Kanyal. "Biochemical and Physiological Effects of Volatile Organic Compounds Emitted by Ocimum Tenuiflorum on Human Stress Biomarker." International Journal of Science, Strategic Management and Technology, vol. 02, no. 04, 2026, pp. . doi:https://doi.org/10.55041/ijsmt.v2i4.302.
Pandey, Vivaswaan, and Sapana Kanyal. "Biochemical and Physiological Effects of Volatile Organic Compounds Emitted by Ocimum Tenuiflorum on Human Stress Biomarker." International Journal of Science, Strategic Management and Technology 02, no. 04 (2026). https://doi.org/https://doi.org/10.55041/ijsmt.v2i4.302.
References
2.Bhattarai, K., Bhattarai, R., Pandey, R. D., Paudel, B., & Bhattarai, H. D. (2024). A comprehensive review of the phytochemical constituents and bioactivities of Ocimum tenuiflorum. The Scientific World Journal, 2024(1), 8895039.
3.Lung, I., Soran, M. L., Opriş, O., Truşcă, M. R. C., Niinemets, Ü., & Copolovici, L. (2016). Induction of stress volatiles and changes in essential oil content and composition upon microwave exposure in the aromatic plant Ocimum basilicum. Science of the Total Environment, 569, 489-495.
4.Olofinsan, K. A., Salau, V. F., Erukainure, O. L., & Islam, M. S. (2021). Ocimum tenuiflorum mitigates iron‐induced testicular toxicity via modulation of redox imbalance, cholinergic and purinergic dysfunctions, and glucose metabolizing enzymes activities. Andrologia, 53(9), e14179.
5.Sarkar, S., & Das, S. (2023). Untargeted metabolomics approach of essential oils to differentiate five
6.Ocimum species and their anti-choline-sterase and anti-tyrosinase activity. Journal of Essential Oil-Bearing Plants, 26(5), 1299-1318.
7.Manjudevi, M., Thirugnanasampandan, R., Vishnupriya, B., & Gogul Ramnath, M. (2022). In vitro propagation of Ocimum sanctum L., Ocimum canum Sims., and Ocimum tenuiflorum L., and evaluation of antioxidant, MMP-9 down regulation of eugenol and camphor. South African Journal of Botany, 151, 208-217.
8.Boulaares, I., Derouiche, S., & Niemann, J. (2025). Phytochemical, GC-MS Analysis and Acute Toxicity Evaluation of Algerian Ocimum basilicum L in Rats. Current Trends in Biotechnology and Pharmacy, 19(1), 2130-2143.
9.Ferreira, O. O., Kumar, R., da Silva, L. R. R., Mali, S. N., Tambe, S., Rosa, U. A., ... & Aguiar, E. H. D. A. (2025). Phytochemistry, pharmacological insights, and food science applications of natural bioactive compounds from Ocimum species with a focus on essential oils. Food Frontiers, 6(5), 2081-2107.
10.Mandal, A. K., Poudel, M., Neupane, N. P., & Verma, A. (2022). Phytochemistry, pharmacology, and applications of Ocimum sanctum (Tulsi). In Edible Plants in Health and Diseases: Volume II: Phytochemical and Pharmacological Properties (pp. 135-174). Singapore: Springer Singapore
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