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FICUS BENJAMINA LEAF EXTRACT MEDIATED ZINC OXIDE NANOPARTICLE AND ITS ANTICANCER ACTIVITY

AUTHORS:
K.Kanagamani
Mentor
Affiliation
Department of Chemistry, SNS College of Technology, Coimbatore-641035, India.
DOI: 10.55041/ijsmt.v2i6.026
CC BY 4.0 License:
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract
Phyto assisted synthesis of metal oxide nanoparticles have been identified as key research area in nanotechnology due to its wide applicability of the nanoparticles in various biomedical fields. The present work explores the biosynthesis of Zinc oxide nanoparticles (ZnO-NPs) using Cassia fistula leaf extract as reducing agent. The synthesized ZnO-NPs was characterized by UV–Vis Spectroscopy (UV–Vis), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectroscopy (EDX), Fourier Transform Infrared spectroscopy (FT-IR), X-ray diffraction (XRD) studies, Transmission Electron Microscopy (TEM) and Selected area electron diffraction (SAED) studies. Biosynthesised ZnO-NPs was found to have Wurtzite hexagonal structure with particle size distributed in the range of 50-200 nm as confirmed by TEM studies. The invitro cytotoxicity studies of biosynthesised ZnO-NPs against DLA cells reveals better antitumor activity of 92% inhibition with concentration of 200 µg/ml of ZnO-NP’s and as the concentration of the ZnO-NPs is increased The anticancer efficiency as well increased.
Keywords
NANOSTRUCTURED MATERIALS CHARACTERISATION ANTICANCER ACTIVITY
Article Information
PUBLICATION DETAILS
Review Type:
Double-Blind Peer Review
License:
CC BY-NC 4.0
Volume/Issue:
Volume 02, Issue 6
Review Rounds:
2
Article Type:
Research Article
Publication Date:
Jun 04 2026
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K.Kanagamani, (2026). Ficus Benjamina leaf extract Mediated Zinc oxide nanoparticle and its Anticancer Activity. International Journal of Science, Strategic Management and Technology, 02(6). https://doi.org/10.55041/ijsmt.v2i6.026

K.Kanagamani, . "Ficus Benjamina leaf extract Mediated Zinc oxide nanoparticle and its Anticancer Activity." International Journal of Science, Strategic Management and Technology, vol. 02, no. 6, 2026, pp. . doi:https://doi.org/10.55041/ijsmt.v2i6.026.

K.Kanagamani, . "Ficus Benjamina leaf extract Mediated Zinc oxide nanoparticle and its Anticancer Activity." International Journal of Science, Strategic Management and Technology 02, no. 6 (2026). https://doi.org/https://doi.org/10.55041/ijsmt.v2i6.026.

References

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  2. L. Wang, Zinc oxide nanostructures: growth, properties and applications. J. Phys. Condens. Matter 2004.

  3. Zhang, M.K. Ram E.K. Stefanakos and D.Y. Goswami, Synthesis, characterization, and applications of ZnO nanowires. J. Nanomater. 2012

  4. Rashidi, A. Ahmadpour F.Bamoharram, S.Zebarjad, M.Heravi and F.Tayari Green biosynthesis and characterization of zinc oxide nanoparticles using Corymbia citriodora leaf extract and their photocatalytic activity. Chem Pap. 2014.

  5. Shukla, E.Agorku,H. Mittaland A. Mishra Synthesis, characterization and photoluminescence properties of Ce3+-doped ZnO-nanophosphors. Chem.Pap. 2014.

  6. Gomez-Solis C, Ballesteros J C,  Torres-Martinez L M, Juarez-Ramirez I,   Diaz Torres LA,  Elvira Zarazua-Morin M, Lee SW. Rapid synthesis of ZnO nano-corncobs from Nital solution and its application in the photodegradation of methyl orange. J.Photochem.Photobiol.A:Chem. 2015

  7. Afifi M, Almaghrabi OA, Kadasa NM. Ameliorative effect of zinc oxide nanoparticles on antioxidants and sperm characteristics in streptozotocin-induced diabetic rat testes. Biomed Res.Int. 2015.

  8. Chen J, Liu X, Wang C, Yin SS, Li XL, Hu WJ, Simon M, Shen ZJ, Ziao Q, Chu CC, Peng X X, Zheng H L. Nitric oxide ameliorates zinc oxide nanoparticles-induced phytotoxicity in rice seedlings. J Hazard Mater. 2015.

  9. Dhandapani P, Siddarth AS, Kamalasekaran S, Maruthamuthu S, Rajagopal G. Bio-approach: ureolytic bacteria mediated synthesis of ZnO nanocrystals on cotton fabric and evaluation of their antibacterial properties. Carbohydr 2014.

  10. Mitra S, Patra P, Pradhan S, Debnath N, Dey KK, Sarkar S, Chattopadhyay D, Goswami A. Microwave synthesis of ZnO@mSiO2 for detailed antifungal mode of action study: understanding the insights into oxidative stress. J Colloid Interface Sci. 2015.

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This article has undergone plagiarism screening and double-blind peer review. Editorial policies have been followed. Authors retain copyright under CC BY-NC 4.0 license. The research complies with ethical standards and institutional guidelines.
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