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ANTICATARACT ACTIVITY OF TRIPHALA BY USING INVITRO GOAT LENS MODEL

AUTHORS:
Ganesh Gunjal
Mrs.Sancheti V.P
Mentor
Manish Ahire, Sagar Vaidya, Dr. Arshu Patel
Affiliation
JES SND institute of pharmacy Babhulagon Yeola
DOI: 10.55041/ijsmt.v2i4.369
CC BY 4.0 License:
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract

Cataracts are a leading cause of blindness and visual impairment worldwide, with oxidative stress and aging being major contributing factors. Triphala, a traditional Ayurvedic polyherbal formulation, has been reported to possess antioxidant, anti-inflammatory, and rejuvenating properties. This study aimed to evaluate the anticataract activity of Triphala on goat lenses. Goat lenses were treated with Triphala extracts at different concentrations (15µg/ml, 30µg/ml, and 60µg/ml) and compared with normal, negative control (glucose 55 mM), and positive control (ascorbic acid 40µg/ml) groups. Total proteins and water-soluble proteins were estimated in all groups. The results showed that Triphala extracts significantly prevented protein aggregation and maintained lens transparency, indicating its potential anticataract activity. These findings suggest that Triphala may be a useful adjunct in the prevention or treatment of cataracts. Further studies are warranted to explore the clinical applications of Triphala in ophthalmology.

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PUBLICATION DETAILS
Review Type:
Double-Blind Peer Review
License:
CC BY-NC 4.0
Volume/Issue:
Volume 02, Issue 04
Review Rounds:
2
Article Type:
Research Article
Publication Date:
Apr 22 2026
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Gunjal, G. & V.P, M. (2026). Anticataract Activity of Triphala by using Invitro Goat Lens Model. International Journal of Science, Strategic Management and Technology, 02(04). https://doi.org/10.55041/ijsmt.v2i4.369

Gunjal, Ganesh, and Mrs.Sancheti V.P. "Anticataract Activity of Triphala by using Invitro Goat Lens Model." International Journal of Science, Strategic Management and Technology, vol. 02, no. 04, 2026, pp. . doi:https://doi.org/10.55041/ijsmt.v2i4.369.

Gunjal, Ganesh, and Mrs.Sancheti V.P. "Anticataract Activity of Triphala by using Invitro Goat Lens Model." International Journal of Science, Strategic Management and Technology 02, no. 04 (2026). https://doi.org/https://doi.org/10.55041/ijsmt.v2i4.369.

References
1.Tewari D, Samoilă O, Gocan D, Mocan A, Moldovan C, Devkota HP, Atanasov AG, Zengin G, Echeverría J, Vodnar D, Szabo B. Medicinal plants and natural products used in cataract management. Frontiers in Pharmacology. 2019 Jun 13;10:466.

2.N. Mahajan K, K. Singhai A, P. Vadnere G. Investigation on anticataract activity of Triphala ghrita. Journal of Chemistry. 2011;8(3):1438-43.

3.Shastry CS, Bharath RK, Aswathanarayana BJ. A Comparative study of Anti-cataract activity of Triphala and its constituents. Int Res J Pharm. 2012;3(5):407-1.

4.Rao P. Antioxidant effect of Triphala-critical review. Journal of Ayurveda and Integrated Medical Sciences. 2017 Feb 28;2(01):213-9.

5.Gowda DV, Muguli G, Rangesh PR, Deshpande RD. Phytochemical and pharmacological actions of Triphala: Ayurvedic formulation-a review. Int J Pharm Sci Rev Res. 2012;15(2):61-5.

6.Jadhav N, Auti S. A BRIEF COMPILATION ON TRIPHALA–A WONDER COMPOUND IN AYURVEDIC OPHTHALMOLOGY.

7.Gupta SK, Kalaiselvan V, Srivastava S, Agrawal SS, Saxena R. Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies. Journal of Ayurveda and Integrative Medicine. 2010 Oct;1(4):280.

8.Prakash S, Shelke AU. Role of Triphala in dentistry. Journal of Indian Society of Periodontology. 2014 Mar 1;18(2):132-5.

9.Jadhav N, Auti S. A BRIEF COMPILATION ON TRIPHALA–A WONDER COMPOUND IN AYURVEDIC OPHTHALMOLOGY

10.Rajagopala M, Dhanisha BK. A Narrative Review of Triphala (fruits of three myrobalans) in Ophthalmology. Annals of Ayurvedic Medicine. 2023 Jul 22;12(1):56-.
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✓ All ethical standards met
This article has undergone plagiarism screening and double-blind peer review. Editorial policies have been followed. Authors retain copyright under CC BY-NC 4.0 license. The research complies with ethical standards and institutional guidelines.
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